Sunday, March 6, 2011

The Immortal Life of Henrietta Lacks

The true story of a woman whose enormous gift to science was shamefully repaid



The scientific story told in Rebecca Skloot's "The Immortal Life of Henrietta Lacks" is marvel enough: Lacks died in 1951, but also lives on in the form of cells, taken from a single biopsy, that have proven easier to grow in a lab than any other human tissue ever sampled. So easy, in fact, that one scientist has estimated that if you could collect all of the cells descended from that first sample on a scale, the total would weigh 50 million metric tons. Lacks' famous cell line, known as HeLa, has played a key role in the development of cures and treatments for polio, AIDS, infertility and cancer, as well as research into cloning, gene mapping and radiation.

There's a run-of-the-mill "The Cells That Changed the World" book in that premise, and one with a better claim to credibility than most of the "Changed the World" titles that have flooded bookstores since Dava Sobel's "Longitude" became a surprise bestseller 14 years ago. But "The Immortal Life of Henrietta Lacks" is far from run-of-the-mill -- it's indelible. Skloot (whom -- full disclosure -- I know slightly) spent a decade tracking down Lacks' surviving family and winning over their much-abused trust, a process that becomes part of the story she tells. Actually, it often takes over the story entirely. Just as the DNA in a cell's nucleus contains the blueprint for an entire organism, so does the story of Henrietta Lacks hold within it the history of medicine and race in America, a history combining equal parts of shame and wonder.

full article: