Friday, August 12, 2011

Pearl Jam


[ed.  I prefer the Mother Love Bone version with Andrew Wood.  After he died, Stone Gossard and Jeff Ament went on to form Pearl Jam and this version of Crown of Thorns is not bad, either. Eddie is great, as always.]
Kurt Cobain
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Iraq Foots the Bill for its Own Destruction

by Murtaza Hussain, Salon

When considering the premise of reparation being paid for the Iraq War it would be natural to assume that the party to whom such payments would be made would be the Iraqi civilian population, the ordinary people who suffered the brunt of the devastation from the fighting. Fought on the false pretence of capturing Saddam Hussein’s nonexistent weapons of mass destruction, the war resulted in massive indiscriminate suffering for Iraqi civilians which continues to this day. Estimates of the number of dead and wounded range from the hundreds of thousands into the millions, and additional millions of refugees remain been forcibly separated from their homes, livelihoods and families. Billions of dollars in reparations are indeed being paid for the Iraq War, but not to Iraqis who lost loved ones or property as a result of the conflict, and who, despite their nation’s oil wealth, are still suffering the effects of an utterly destroyed economy. "Reparations payments" are being made by Iraq to Americans and others for the suffering which those parties experienced as a result of the past two decades of conflict with Iraq.

In addition to making hundreds of millions of dollars in reparation payments to the United States, Iraq has been paying similarly huge sums to corporations whose business suffered as a result of the actions of Saddam Hussein. While millions of ordinary Iraqis continue to lack even reliable access to drinking water, their free and representative government has been paying damages to corporations such as Pepsi, Philip Morris and Sheraton; ostensibly for the terrible hardships their shareholders endured due to the disruption in the business environment resulting from the Gulf War. When viewed against the backdrop of massive privatization of Iraqi natural resources, the image that takes shape is that of corporate pillaging of a destroyed country made possible by military force.

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Gallows


[ed.  Seems pretty relevant given recent events.  Read The Great Splintering.]

Smartphones of the Future

by Ginny Miles

As you're reading this article, developers, engineers, and product designers are working on the next great mobile technology. The mobile world is rapidly changing: Smartphones have gone from portable messaging and email devices to streaming-video machines that surf the Web at blazing speed and have cameras that rival point-and-shoots (and they also happen to make calls). What will smartphones look like in five years? Or ten? What sort of amazing things will they be able to do?

Of course, we have no way to predict exactly how cell phones will evolve (unless some sort of magical crystal ball comes along), but looking at today’s trends and tracking what the geniuses at MIT and other academic institutions are up to can give us a pretty good idea of what’s to come.

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'Huge' Results Raise Hope for Cancer Breakthrough

by Eryn Brown, LA Times

In a potential breakthrough in cancer research, scientists at the University of Pennsylvania have genetically engineered patients' T cells — a type of white blood cell — to attack cancer cells in advanced cases of a common type of leukemia.

Two of the three patients who received doses of the designer T cells in a clinical trial have remained cancer-free for more than a year, the researchers said.

Experts not connected with the trial said the feat was important because it suggested that T cells could be tweaked to kill a range of cancers, including ones of the blood, breast and colon.

"This is a huge accomplishment — huge," said Dr. Lee M. Nadler, dean for clinical and translational research at Harvard Medical School, who discovered the molecule on cancer cells that the Pennsylvania team's engineered T cells target.

Findings of the trial were reported Wednesday in two journals.

To build the cancer-attacking cells, the researchers modified a virus to carry instructions for making a molecule that binds with leukemia cells and directs T cells to kill them. Then they drew blood from three patients who suffered from chronic lymphocytic leukemia and infected their T cells with the virus.

When they infused the blood back into the patients, the engineered T cells successfully eradicated cancer cells, multiplied to more than 1,000 times in number and survived for months. They even produced dormant "memory" T cells that might spring back to life if the cancer was to return.

"We knew [the therapy] could be very potent," said Dr. David Porter, director of the blood and marrow transplantation program at the Hospital of the University of Pennsylvania in Philadelphia and a coauthor of both papers, which were published in the New England Journal of Medicine and Science Translational Medicine. "But I don't think we expected it to be this dramatic on this go-around."

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Thursday, August 11, 2011

 
Ryan Kapp, Skokie Night, silkscreen on archival paper; 24 x 20", edition of 125

Damien Rice


The Patent System Isn't Broken - We Are

[ed.  Two patent articles in one day (you might conclude that I've been sensitized to patent and copyright issues lately, and you would be right - see the Note and Interesting Article link on the sidebar).  But, wow, this article is impressive.  Great essay on the history, function and use of patents and how they affect intellectual property and technical innovation.]

by Nilay Patel

There is a fundamental problem with patents in the United States.

It is us.

By that I mean all of us: the companies and people who directly interact with the patent system, the media that reports on those interactions, the analysts and experts who inform the media, and finally the large, active, and vocal readership that we try and service with our reporting. As a group, we have accepted and let lie the lazy conventional wisdom that the patent system is broken beyond repair, a relic of a previous time that has been obsoleted by the rapid pace of technical innovation, particularly in software, and that it should perhaps be scrapped altogether.

In the past few months, this rhetoric has grown to a furious roar, as the patent system seems to be affecting more and more of the technology industry in a negative way: small mobile app developers have been targeted with spurious lawsuits from companies that make nothing, major players like Apple, HTC, and Samsung are locked in patent-related litigation, and a pair of multibillion-dollar patent auctions has sparked an unprecedented war of words between Microsoft and Google. The most passionate critics loudly argue that whatever benefits our current patent system might offer have now been exceeded by its costs; that resources that should otherwise go to the development of new ideas are instead being misspent on the overzealous protection of the old.

This line of thinking has been so forcefully and insistently repeated that it has become almost axiomatic, an intellectual and rhetorical cheat that is rarely (if ever) questioned. But it’s also wrong — painfully wrong, in ways that sabotage any real attempt at reform. Being loud and angry is a great way to get attention, but it’s a terrible way to actually get anything done — especially since most of the emphatic chest-pounding sounds like a slightly dumber version of an argument we’ve been having in this country since Thomas Jefferson was appointed the first head of the Patent Office.

So let’s start over, shall we? Let’s actually look at how the patent system works, where it’s specifically malfunctioning, and how we can fix it. Ready? Let’s go.

The patent exchange

The core public policy behind the patent system is widely ignored, even though it’s extremely simple and really quite clever. Patents are more than just a simple incentive for people to develop new inventions — they’re actually an exchange between inventors and the public. In exchange for a time-limited monopoly on their inventions, inventors must fully disclose the invention itself in the patent specification, and agree to release their work into the public domain once their monopoly runs out. The rules for disclosure are laid out in 35 U.S.C. § 112, and they’re fairly strict: the specification must be detailed enough so that anyone with “ordinary skill in the art” of the invention can build the claimed technology, and they must also disclose the “best mode” of building the invention. Breaking the rules can have severe consequences, since a patent that doesn’t adequately disclose the claimed invention can be ruled invalid. And since patent specifications fall into the public domain once the patent expires, we get a huge and constantly-growing vault of fully-disclosed technology that anyone can use to build new products.

Let’s think about what that means in practice. Here’s US patent #6,285,999, which is Larry Page’s patent on PageRank, the core algorithm that powers Google search. Because getting a patent means Page had to fully disclose the technology, we can go right ahead and look at some of the math behind one of the most important and disruptive inventions in the history of the world.


(Remember, this isn’t what’s actually patented — it’s just the required specification that supports the patent claims.) Because getting a patent means accepting a time-limited monopoly on your invention, anyone will be able to use this specification to build their own search engine when the patent expires in 2018. In the meantime, you’re free to look at Google’s work and attempt to design around the specific claims in the patent. That’s an important way the patent system encourages innovation, actually: it forces inventors to build alternative ways to do things. You can bet Microsoft’s Bing team has spent hours studying the PageRank patent in an attempt to build something that works differently — and hopefully better.

Seu Jorge


[ed.  Sorry, no video, but this has the best sound quality.  David Bowie's Rebel Rebel.  Why does everything sound more sensuous in French?]

Inside Pfizer's Palace Coup

by Peter Elkind and Jennifer Reingold

For Jeff Kindler, it was a humiliating moment. The CEO of Pfizer, the world's largest pharmaceutical company, had been summoned to the airport in Fort Myers, Fla., on Saturday, Dec. 4, 2010, for a highly unusual purpose: to plead for his job.

Three stone-faced directors, representing the company's board, sat inside a drab airport conference room as the CEO, trained as a trial lawyer, struggled to argue his most important case. Alerted to this meeting less than 24 hours earlier, Kindler detailed his accomplishments, speaking nonstop for the better part of an hour. He touted his bold reorganizations, praised his administration's sweeping cost reductions, and rhapsodized about his reinvention of Pfizer's crucial research-and-development operations.

But the three board members, Constance Horner, a former deputy secretary at the U.S. Department of Health and Human Services; George Lorch, an ex-CEO of Armstrong World Holdings; and Bill Gray, a former Philadelphia congressman, weren't there to debate the direction of the company. The board had spent a frantic week in an urgent investigation: A revolt had erupted against Kindler among a handful of senior managers, and the directors were trying to figure out what was going on. One possibility: an internal power grab. Another: a CEO who was unraveling.

As the meeting continued -- it lasted more than two hours -- it became clear that Kindler had little chance of saving his job. Perhaps, he finally said, it was time for him to resign. The directors, who seemed ready for this suggestion, told Kindler they were prepared to give him a far more generous settlement package if he didn't take the fight to the full board. Kindler agreed to think it over and flew home.

A day later, in an unusual Sunday night announcement, the 55-year-old CEO retired, effective immediately. Pfizer's press release offered a surprisingly candid explanation, which was inserted by Kindler himself: "The combination of meeting the requirements of our many shareholders around the world and the 24/7 nature of my responsibilities has made this period extremely demanding on me personally."

As revealing as it was, that statement only hinted at the turmoil inside Pfizer (PFE). Indeed, what has occurred at the company -- whose $68 billion in annual sales are built on blockbuster drugs such as Lipitor and Viagra -- is extraordinary. Once a Wall Street darling and corporate icon, Pfizer has tumbled into disarray. In the decade that ended with Kindler's departure, its stock price sagged from a high of $49 down to $17 and its drug pipeline dried up (problems the company continues to grapple with today). Pfizer lost its way, stumbling through a frantic series of zigzags in the hopes of finding new blockbusters to sustain its prodigious profits in the future.

Meanwhile, its managers descended into behavior that would do Shakespeare -- or Machiavelli -- proud. There was the ex-CEO who couldn't relinquish his power and quietly maneuvered to undercut two successors he had helped install. Then there was the human resources chief who divided the staff rather than uniting it. Most of all, there was Kindler himself, a bright man with some fresh ideas for reforming Pfizer but a person who agonized over decisions even as he second-guessed everybody else's actions. The story of Jeff Kindler's tumultuous tenure at Pfizer is a saga of ambition, intrigue, backstabbing, and betrayal -- all of it exacerbated by a board that allowed the problems to fester for years.

The full story of Kindler's downfall has never before been told. Fortune reported this article for four months, interviewing 102 people, including executives and directors who worked closely with him at Pfizer and at previous stages of his career. For their parts, both Kindler and the company say that they are bound by a confidentiality agreement they signed as part of Kindler's departure.

Kindler declined to speak about Pfizer, but a representative provided a written statement: "Pfizer is a great company I was privileged to serve for nine years. I am proud of what our team accomplished and delighted to see [new CEO Ian Read], together with the business and scientific leaders we brought together, continue to build on these achievements." In its own statement, the drug company told Fortune: "We thank Jeff Kindler for his many years of service to Pfizer," noting that "Jeff came into the industry at a tumultuous time and faced significant challenges such as patent expirations of some of our major products .… We wish Jeff well in all of his future endeavors."

In the end, the story of Jeff Kindler's time at Pfizer provides a window into the challenges facing a mammoth company in an essential industry -- and the people who aspire to govern it. Pfizer is an enterprise with the noble calling of easing pain and curing disease. Yet its leaders spent much of their time in the tawdry business of turf wars and political scheming.

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The Motorcycle Gangs

[ed.  Slow news day today: just stuff about rioting, revolutions, collapsing economies, starving multitudes, endless wars, venal politicians and rapacious bankers. Ho hum, eh?  So here's an essay from Hunter S. Thompson, circa 1965, about the Hell's Angels. What makes this seem relevant today is how easy it is to substitute our current bogeymen - terrorists, illegal immigrants, minorities in general - and feel the same dynamic playing out in our media, over and over again.]   

by Hunter S. Thompson

Last Labor Day weekend newspapers all over California gave front-page reports of a heinous gang rape in the moonlit sand dunes near the town of Seaside on the Monterey Peninsula. Two girls, aged 14 and 15, were allegedly taken from their dates by a gang of filthy, frenzied, boozed-up motorcycle hoodlums called "Hell's Angels," and dragged off to be "repeatedly assaulted."

A deputy sheriff, summoned by one of the erstwhile dates, said he "arrived at the beach and saw a huge bonfire surrounded by cyclists of both sexes. Then the two sobbing, near-hysterical girls staggered out of the darkness, begging for help. One was completely nude and the other had on only a torn sweater."

Some 300 Hell's Angels were gathered in the Seaside-Monterey area at the time, having convened, they said, for the purpose of raising funds among themselves to send the body of a former member, killed in an accident, back to his mother in North Carolina. One of the Angels, hip enough to falsely identify himself as "Frenchy of San Bernardino," told a reporter who came out to meet the cyclists: "We chose Monterey because we get treated good here; most other places we get thrown out of town."

But Frenchy spoke too soon. The Angels weren't on the peninsula twenty-four hours before four of them were in jail for rape, and the rest of the troop was being escorted to the county line by a large police contingent. Several were quoted, somewhat derisively, as saying: "That rape charge against our guys is phony and it won't stick."

It turned out to be true, but that was another story and certainly no headliner. The difference between the Hell's Angels in the paper and the Hell's Angels for real is enough to make a man wonder what newsprint is for. It also raises a question as to who are the real hell's angels.

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Eat More Fiber

squirrelmuncher.jpg

Level 3 Communications, a fiber network company with 84,000 miles of cable, comes clean about the real danger to its business 

By Alexis Madrigal

Among the enemies of the future, we should count the common squirrel. According to Level 3 Communications, which maintains an 84,000-mile fiber network, the cute rodents do 17 percent of the damage to their fiber optic network.

Fred Lawler, a company vice president who "is passionate about fiber protection," wrote about the "furry little nut eater" problem in a blog post for Level 3.
Of all the animals in the whole world, almost all of our animal damage comes from this furry little nut eater. Squirrel chews account for a whopping 17% of our damages so far this year! But let me add that it is down from 28% just last year and it continues to decrease since we added cable guards to our plant. Honestly, I don't understand what the big attraction is or why they feel compelled to gnaw through cables. Our guys in the field have given this some thought and jokingly suspect the cable manufacturers of using peanut oil in the sheathing. If you have any new ideas on how we can combat these wayward rodents, I'd love to hear from you. We are always looking for ways to improve.
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Edward Kienholz. Back Seat Dodge ‘38. 1964
Kienholz’s decision to preserve the grimy, used quality of this truncated 1938 Dodge is typical of his assemblages, which are made of found materials and often explore sensitive social topics. The artist chose to incorporate this particular model of car into the work because he recalled a similar teenage experience in the back of his father’s ’38 Dodge. When this work was shown in an exhibition here at LACMA in 1966, the Los Angeles County Board of Supervisors demanded that the sculpture be removed from view because it was “pornographic.” Though the sculpture ultimately remained in the show, the controversy surrounding its exhibition echoed public obscenity cases heard in the Supreme Court throughout the 1960s.
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Patent Trolls

by Rob Beschizza

News aggregator Fark, targeted by a company owning a patent covering "news releases", settled its case for $0. Fark proprietor Drew Curtis writes about what sounds like an unusually callous and disinterested shakedown.
The patent troll realized we were going to fight them instead of settle, so they asked for our best offer. I said how about you get nothing and drop the lawsuit? They accepted. 
The patent covered a method for inputting news releases into a web form, which would then compile the news release and email it to media outlets. Now, aside from the fact that a ton of prior art exists and that the patent should never have been awarded in the first place, Fark and all the other websites named in the lawsuit don't produce "news releases". In the world of journalism, the term "news release" is equivalent to "press release" - the patent itself equates the two in the opening description. Could a judge have ruled otherwise? Sure. They've been known to rule that the sky is green - which is why this lawsuit was dangerous.
News release, news story, blog post ... what's the difference? Curtis notes that it's already cost a lot of money, and that it would cost millions to try and recover it.

The patent troll, Gooseberry Natural Resources, also sued TechCrunch and many others; Reddit and Yahoo have settled, but AOL is apparently fighting on.

via:

More here:  Patent Trolls Come in All Shapes and Sizes 

And here:  When Startups Fail

It’s the Economy, Dummkopf!

With Greece and Ireland in economic shreds, while Portugal, Spain, and perhaps even Italy head south, only one nation can save Europe from financial Armageddon: a highly reluctant Germany. The ironies—like the fact that bankers from Düsseldorf were the ultimate patsies in Wall Street’s con game—pile up quickly as Michael Lewis investigates German attitudes toward money, excrement, and the country’s Nazi past, all of which help explain its peculiar new status.

by Michael Lewis

By the time I arrived in Hamburg the fate of the financial universe seemed to turn on which way the German people jumped. Moody’s was set to downgrade the Portuguese government’s debt to junk-bond status, and Standard & Poor’s had hinted darkly that Italy might be next. Ireland was about to be downgraded to junk status, too, and there was a very real possibility that the newly elected Spanish government might seize the moment to announce that the old Spanish government had miscalculated, and owed foreigners a lot more money than they previously imagined. Then there was Greece. Of the 126 countries with rated debt, Greece now ranked 126th: the Greeks were officially regarded as the least likely people on the planet to repay their debts. As the Germans were not only the biggest creditor of the various deadbeat European nations but their only serious hope for future funding, it was left to Germans to act as moral arbiter, to decide which financial behaviors would be tolerated and which would not. As a senior official at the Bundesbank put it to me, “If we say ‘no,’ it’s ‘no.’ Nothing happens without Germany. This is where the losses come to live.” Just a year ago, when German public figures called Greeks cheaters, and German magazines ran headlines like WHY DON"T YOU SELL YOUR ISLANDS, YOU BANKRUPT GREEKS? ordinary Greeks took it as an outrageous insult. In June of this year the Greek government started selling islands or at any rate created a fire-sale list of a thousand properties—golf courses, beaches, airports, farmlands, roads—that they hoped to sell, to help repay their debts. It was safe to say that the idea for doing this had not come from the Greeks.

To no one but a German is Hamburg an obvious place to spend a vacation, but it happened to be a German holiday, and Hamburg was overrun by German tourists. When I asked the hotel concierge what there was to see in his city, he had to think for a few seconds before he said, “Most people just go to the Reeperbahn.” The Reeperbahn is Hamburg’s red-light district, the largest red-light district in Europe, according to one guidebook, though you have to wonder how anyone figured that out. And the Reeperbahn, as it happens, was why I was there.

Perhaps because they have such a gift for creating difficulties with non-Germans, the Germans have been on the receiving end of many scholarly attempts to understand their collective behavior. In this vast and growing enterprise, a small book with a funny title towers over many larger, more ponderous ones. Published in 1984 by a distinguished anthropologist named Alan Dundes, Life Is Like a Chicken Coop Ladder set out to describe the German character through the stories that ordinary Germans liked to tell one another. Dundes specialized in folklore, and in German folklore, as he put it, “one finds an inordinate number of texts concerned with anality. Scheisse (shit), Dreck (dirt), Mist (manure), Arsch (ass).… Folksongs, folktales, proverbs, riddles, folk speech—all attest to the Germans’ longstanding special interest in this area of human activity.”

The Hamburg red-light district had caught Dundes’s eye because the locals made such a big deal of mud-wrestling. Naked women fought in a metaphorical ring of filth while the spectators wore plastic caps, a sort of head condom, to avoid being splattered. “Thus,” wrote Dundes, “the audience can remain clean while enjoying dirt!” Germans longed to be near the shit, but not in it. This, as it turns out, was an excellent description of their role in the current financial crisis.

The Scheisse Hits the Fan

A week or so earlier, in Berlin, I had gone to see Germany’s deputy minister of finance, a 44-year-old career government official named Jörg Asmussen. The Germans are now in possession of the only Finance Ministry in the big-time developed world whose leaders don’t need to worry whether their economy will collapse the moment investors stop buying their bonds. As unemployment in Greece climbs to the highest on record (16.2 percent at last count), it falls in Germany to 20-year lows (6.9 percent). Germany appears to have experienced a financial crisis without economic consequences. They’d donned head condoms in the presence of their bankers, and so they had avoided being splattered by their mud. As a result, for the past year or so the financial markets have been trying and failing to get a bead on the German people: they can probably afford to pay off the debts of their fellow Europeans, but will they actually do it? Are they now Europeans, or are they still Germans? Any utterance or gesture by any German official anywhere near this decision for the past 18 months has been a market-moving headline, and there have been plenty, most of them echoing German public opinion, and expressing incomprehension and outrage that other peoples can behave so irresponsibly. Asmussen is one of the Germans now being obsessively watched. He and his boss, Wolfgang Schäuble, are the two German officials present in every conversation between the German government and the deadbeats.

The Finance Ministry, built in the mid-1930s, is a monument to both the Nazis’ ambition and their taste. A faceless butte, it is so big that if you circle it in the wrong direction it can take you 20 minutes to find the front door. I circle it in the wrong direction, then sweat and huff to make up for lost time, all the while wondering if provincial Nazis in from the sticks had had the same experience, wandering outside these forbidding stone walls and trying to figure out how to get in. At length I find a familiar-looking courtyard: the only difference between it and famous old photographs of it is that Hitler is no longer marching in and out of the front door, and the statues of eagles perched atop swastikas have been removed. “It was built for Göring’s Air Ministry,” says the waiting Finance Ministry public-relations man, who is, oddly enough, French. “You can tell from the cheerful architecture.” He then explains that the building is so big because Hermann Göring wanted to be able to land planes on its roof.

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