The scientist at the heart of the scandal involving the world’s first gene-edited babies has said he moved “too quickly” by pressing ahead with the procedure.
He Jiankui sent shock waves across the world of science when he announced in 2018 that he had edited the genes of twin girls, Lulu and Nana, before birth. He was subsequently sacked by his university in Shenzhen, received a three-year prison sentence, and was broadly condemned for having gone ahead with the risky, ethically contentious and medically unjustified procedure with inadequate consent from the families involved.
Speaking to the Guardian in one of his first interviews since his public re-emergence last year, He said: “I’ve been thinking about what I’ve done in the past for a long time. To summarise it up in one sentence: I did it too quickly.”
However, he stopped short of expressing regret or apologising, saying “I need more time to think about that” and “that’s a complicated question”. (...)
Gene-edited cells were already beginning to be used in clinical treatments for adults. But genetically modifying embryos was – and is – far more ethically contentious, because changes are made to every cell in the body and are passed down to subsequent generations. Some question whether such a step could ever be medically justified.
Against this backdrop, He dropped the bombshell at an international conference in Hong Kong four years ago that he had modified two embryos before they were placed in their mother’s womb. It later emerged that a third gene-edited baby had been born. (...)
“According to Chinese law, when a person has served the prison [sentence], after that they begin again with full rights,” he said. “Compared to the past experience, it’s more important what we’re doing today that determine whether I move on or not.”
Asked whether the past four years had been difficult, He said he preferred to focus on the future. “I like the Beatles song Let It Be,” he said. “Let’s move on to my new project.”