Thursday, April 25, 2024

The Rise and Impending Fall of the Dental Cavity

[ed. More information than I care to know (or untangle) about a promising new bacterial treatment that appears to (somewhat - maybe completely) eliminate cavities. You can read the back story and debates here and in the links below. Form your own conclusions.]


Brighter Smiles Through Biotechnology

If you’ve been on Twitter lately, you might have seen when I made this post:

I’m one of the latest people to have had this wonderful living caries vaccine applied to their teeth. Given the incredible human toll of caries, you might be wondering when you, too, can get this healthier form of S. mutans in your mouth.

The answer is now. Orders just went live and you can place them here for just $250.

BCS3-L1 will soon be home-delivered in the U.S. for the price of a single dental filling, and there are plans to expand to other locations in the works too. The scourge of poor dental health that has wracked humanity for 10,000 years might soon be behind us.

A lucky part of all of this is that we’ll only need to try our hand at eradication once.

Like smallpox, S. mutans doesn’t have some natural reservoir that will crop up to re-infect humans with a wild strain that brings caries back. After we’ve gotten rid of it, it’s likely that caries will simply be diminished to the point of irrelevance for the vast majority of mankind. What’s more, because of the parent-to-child transmission described at this article’s outset, if a would-be parent is colonized, their kids will end up living a life that’s likely to include far fewer or zero caries.

The benefits for the poor, the old, infirm, and incapable of taking care of themselves, and the Third World are so large that there ought to be a public health initiative to spread this around. Such an effort would ultimately save many billions of dollars and hundreds of thousands, millions, or—in the long-enough run—potentially billions of human lives.

If you would like to read more about BCS3-L1 (also known as Lumina or SMaRT), please see Defying Cavity on AstralCodexTen. [ed. Here: Defying Cavity: Lantern Bioworks FAQ; and, Updates on Lumina Probiotic (ACX).]

by Cremieux, Cremieux Recueil |  Read more:
Images: Cross et al. (2009); Twitter/X